Helena Jehnichen April 23, 2023 IBS What are the 4 mental responses to stress? Helena Jehnichen April 23, 2023 IBS When you are having an IBS flareup, your body may be responding to STRESS.What are the 4 mental responses to stress? 1) Restlessness (nervousness)2) Sadness3) Moodiness4) Grief or DepressionHow does your body deal with these emotions?